MolNFT v1 · #2300 · protein
Crystal structural analysis of mutations in the hydrophobic cores of barnase
1BSD: “Crystal structural analysis of mutations in the hydrophobic cores of barnase”. X-ray diffraction, 2 pockets (best druggability 0.40). MolNFT v1 #2300 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1BSD
- Type
- protein
- Length
- 321 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Barnase
- EC
- 3.1.27.-
- UniProt
- P00648
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 23% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Barnase (EC 3.1.27.-) | protein | 107 | 23% helix, 23% strand | P00648 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.40 | 0.73 | 26 | empty |
| 2 | 58 | 0.28 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 199 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 1BSD · Crystal structural analysis of mutations in the hydrophobic cores of barnase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00648
- Elsewhere: RCSB PDB 1BSD · PDBe 1BSD · UniProt P00648
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