MolNFT v1 · #22929 · protein

Solution structure of cappd*, an independently folded extracellular domain of human amyloid-beta precursor protein

1TKN · Amyloid beta A4 protein: “Solution structure of cappd*, an independently folded extracellular domain of human amyloid-beta precursor…”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #22929 on GenesisL1: 3D structure…

PDB: 1TKN
Type: protein
Length: 110 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Amyloid beta A4 protein
UniProt: P05067
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 90% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Amyloid beta A4 protein	protein	110	90% helix, 0% strand	P05067

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.32	0.75	16	empty

Compared structures

1TKN · Solution structure of CAPPD*, an independently folded extracellular domain of human… · the same entry in another collection · chain A against A, TM-score 1.00
P05067 · AlphaFold monomer V2.0 prediction for amyloid-beta precursor protein (P05067) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05067
Elsewhere: RCSB PDB 1TKN · PDBe 1TKN · UniProt P05067

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