MolNFT v1 · #22648 · protein
Crystal structure of yeast tata-binding protein and model for interaction with DNA
1TBP: “Crystal structure of yeast tata-binding protein and model for interaction with DNA”. X-ray diffraction, 3 pockets (best druggability 0.59). MolNFT v1 #22648 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1TBP
- Type
- protein
- Length
- 360 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tata-binding protein
- UniProt
- P13393
- Pockets
- 3 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 25% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Tata-binding protein | protein | 180 | 25% helix, 33% strand | P13393 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 198 | 0.59 | 0.81 | 37 | empty |
| 2 | 201 | 0.52 | 0.77 | 37 | empty |
| 3 | 70 | 0.30 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1445 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 1TBP · Crystal structure of yeast tata-binding protein and model for interaction with DNA · the same entry in another collection · chain A against A, TM-score 1.00
- P13393 · AlphaFold monomer V2.0 prediction for tata-box-binding protein (P13393) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13393
- Elsewhere: RCSB PDB 1TBP · PDBe 1TBP · UniProt P13393
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