MolNFT v1 · #22350 · protein

Solution structure of the PDZ domain of af-6

1T2M · Af-6 protein: “Solution structure of the PDZ domain of af-6”. Solution nmr, 1 pocket (best druggability 0.70). MolNFT v1 #22350 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1T2M
Type: protein
Length: 93 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Af-6 protein
UniProt: P55196
Pockets: 1 · best druggability 0.70

Structure

solution nmr · 1 distinct chain · 15% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Af-6 protein	protein	93	15% helix, 40% strand	P55196

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	74	0.70	0.95	24	empty

Compared structures

1T2M · Solution Structure Of The Pdz Domain Of AF-6 · the same entry in another collection · chain A against A, TM-score 1.00
P55196 · AlphaFold monomer V2.0 prediction for afadin (P55196) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55196
Elsewhere: RCSB PDB 1T2M · PDBe 1T2M · UniProt P55196

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