UniProt P55196
Afadin (P55196)
Afadin (UniProt P55196): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55196
- Protein
- Afadin
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
11 records of P55196 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T2M | Solution Structure Of The Pdz Domain Of AF-6 | solution nmr | A | — | — |
| 1T2M | Solution structure of the PDZ domain of af-6 | solution nmr | A | — | — |
| 2AIN | Solution structure of the AF-6 PDZ domain complexed with the C-terminal peptide from the Bcr protein | solution nmr | A | — | — |
| 2AIN | Solution structure of the af-6 PDZ domain complexed with the C- terminal peptide from the BCR… | solution nmr | A | — | — |
| 2EXG | Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6… | solution nmr | A | — | — |
| 2EXG | Making protein-protein interactions drugable: discovery of low- molecular-weight ligands for the… | solution nmr | A | — | — |
| 5A6C | Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation | x-ray diffraction | A, B | — | — |
| 5A6C | Concomitant binding of afadin to lgn and F-actin directs planar spindle orientation | x-ray diffraction | A, B | — | — |
| 7QCR | MLLT4/Afadin PDZ domain in complex with the C-terminal peptide from protein E of SARS-CoV-2 | x-ray diffraction | A, B | SO4 | 1 (best 0.60) |
| 7QCR | MLLT4/AFADIN PDZ domain in complex with the C-terminal peptide from protein E of SARS-cov-2 | x-ray diffraction | A, B | SO4 | — |
| P55196 | AlphaFold monomer V2.0 prediction for afadin (P55196) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 1T2M chain A against the predicted model P55196: TM-score 0.90, RMSD 1.32 Å
- 1T2M chain A against the predicted model P55196: TM-score 0.90, RMSD 1.32 Å
- 5A6C chain A against the predicted model P81274: TM-score 0.88, RMSD 2.57 Å
- 5A6C chain A against the predicted model P81274: TM-score 0.88, RMSD 2.57 Å
- 5A6C chain B against the predicted model P81274: TM-score 0.88, RMSD 2.57 Å
- 5A6C chain B against the predicted model P81274: TM-score 0.88, RMSD 2.57 Å
- 2AIN chain A against the predicted model P55196: TM-score 0.86, RMSD 1.68 Å
- 2AIN chain A against the predicted model P55196: TM-score 0.86, RMSD 1.68 Å
- 7QCR chain B against the predicted model P55196: TM-score 0.85, RMSD 1.15 Å
- 7QCR chain B against the predicted model P55196: TM-score 0.85, RMSD 1.15 Å
Elsewhere
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