MolNFT v1 · #21551 · protein

Staphylococcal enterotoxin B complexed with lactose

1SE4: “Staphylococcal enterotoxin B complexed with lactose”. X-ray diffraction, 2 ligands (BGC, GAL), 1 pocket (best druggability 0.42). MolNFT v1 #21551 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1SE4
Type: protein
Length: 239 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Staphylococcal enterotoxin B
UniProt: P01552
Ligands: BGC, GAL
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 17% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Staphylococcal enterotoxin B	protein	239	17% helix, 38% strand	P01552

Ligands and binding sites

BGC · beta-D-glucopyranose · sugar · chains A
GAL · beta-D-galactopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.42	0.79	20	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1SE4 · Staphylococcal enterotoxin B complexed with lactose · the same entry in another collection · chain A against A, TM-score 1.00
P01552 · AlphaFold monomer V2.0 prediction for enterotoxin type B (P01552) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01552
Elsewhere: RCSB PDB 1SE4 · PDBe 1SE4 · UniProt P01552

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