MolNFT v1 · #21115 · protein
Large increases in general stability for subtilisin BPN(PRIME) through incremental changes in the free energy of unfolding
1S01 · Subtilisin bpn': “Large increases in general stability for subtilisin BPN(PRIME) through incremental changes in the free energy…”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.40). MolNFT v1 #21115 on GenesisL1…
- PDB
- 1S01
- Type
- protein
- Length
- 275 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Subtilisin bpn'
- EC
- 3.4.21.62
- UniProt
- P00782
- Ligands
- CA
- Pockets
- 1 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Subtilisin bpn' (EC 3.4.21.62) | protein | 275 | 30% helix, 20% strand | P00782 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 111 | 0.40 | 0.76 | 28 | empty |
Modifications
Observed in the structure: 1 modified (methylation).
Compared structures
- 1S01 · Large increases in general stability for subtilisin BPN(PRIME) through incremental… · the same entry in another collection · chain A against A, TM-score 1.00
- P00782 · AlphaFold monomer V2.0 prediction for subtilisin bpn' (P00782) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00782
- Elsewhere: RCSB PDB 1S01 · PDBe 1S01 · UniProt P00782
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