MolNFT v1 · #20819 · protein
Spatial model of L7 dimer from E.COLI with one hinge region in helical state
1RQV · 50S ribosomal protein L7/L12: “Spatial model of L7 dimer from E.COLI with one hinge region in helical state”. Solution nmr, 1 pocket (best druggability 0.68). MolNFT v1 #20819 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1RQV
- Type
- protein
- Length
- 240 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 50S ribosomal protein L7/L12
- UniProt
- P0A7K2
- Pockets
- 1 · best druggability 0.68
Structure
solution nmr · 1 distinct chain · 62% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 50S ribosomal protein L7/L12 | protein | 120 | 62% helix, 15% strand | P0A7K2 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 143 | 0.68 | 0.88 | 32 | empty |
Interfaces
1 interface between chains.
- A–B · 975 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 1RQV · Spatial model of L7 dimer from E.coli with one hinge region in helical state · the same entry in another collection · chain A against A, TM-score 1.00
- P0A7K2 · AlphaFold monomer V2.0 prediction for 50S ribosomal protein L7/L12 (P0A7K2) · a predicted model of the same protein · chain A against A, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A7K2
- Elsewhere: RCSB PDB 1RQV · PDBe 1RQV · UniProt P0A7K2
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