MolNFT v1 · #20408 · protein
Actin crystal dynamics: structural implications for F-actin nucleation, polymerization and branching mediated by the anti-parallel dimer
1RDW · Actin, alpha skeletal muscle: “Actin crystal dynamics: structural implications for F-actin nucleation, polymerization and branching mediated…”. X-ray diffraction, 3 ligands (ATP, LAR, MG), 2 pockets (best druggability 0.74). MolNFT…
- PDB
- 1RDW
- Type
- protein
- Length
- 361 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Actin, alpha skeletal muscle
- UniProt
- P68135
- Ligands
- ATP, LAR, MG
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Actin, alpha skeletal muscle | protein | 361 | 44% helix, 20% strand | P68135 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · chains X
- LAR · Latrunculin A · ligand · chains X
- MG · Magnesium ion · metal · 2 copies · chains X
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 465 | 0.74 | 0.83 | 51 | MG, ATP, LAR |
| 2 | 129 | 0.53 | 0.81 | 21 | empty |
Compared structures
- 1RDW · Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization… · the same entry in another collection · chain X against X, TM-score 1.00
- P68135 · AlphaFold monomer V2.0 prediction for actin, alpha skeletal muscle (P68135) · a predicted model of the same protein · chain X against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P68135
- Elsewhere: RCSB PDB 1RDW · PDBe 1RDW · UniProt P68135
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.