MolNFT v1 · #20307 · protein

Recombinant avidin

1RAV: “Recombinant avidin”. X-ray diffraction, 3 pockets (best druggability 0.53). MolNFT v1 #20307 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1RAV
Type: protein
Length: 248 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Avidin
UniProt: P02701
Pockets: 3 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Avidin	protein	124	7% helix, 50% strand	P02701

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	215	0.53	0.77	31	empty
2	96	0.46	0.79	14	empty
3	55	0.28	0.74	12	empty

Interfaces

1 interface between chains.

A–B · 139 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1RAV · Recombinant avidin · the same entry in another collection · chain A against A, TM-score 1.00
P02701 · AlphaFold monomer V2.0 prediction for avidin (P02701) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02701
Elsewhere: RCSB PDB 1RAV · PDBe 1RAV · UniProt P02701

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