MolNFT v1 · #19835 · protein

Crystal structure of a family 51 alpha-L-arabinofuranosidase in complex with ara-ALPHA(1,3)-xyl

1QW8: “Crystal structure of a family 51 alpha-L-arabinofuranosidase in complex with ara-ALPHA(1,3)-xyl”. X-ray diffraction, 2 ligands (XYP, AHR), 6 pockets (best druggability 0.69). MolNFT v1 #19835 on GenesisL1: 3D structure, binding…

PDB: 1QW8
Type: protein
Length: 994 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-L-arabinofuranosidase
EC: 3.2.1.55
UniProt: Q9XBQ3
Ligands: XYP, AHR
Pockets: 6 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Alpha-L-arabinofuranosidase (EC 3.2.1.55)	protein	497	29% helix, 27% strand	Q9XBQ3

Ligands and binding sites

XYP · beta-D-xylopyranose · sugar · 2 copies · chains A, B
AHR · alpha-L-arabinofuranose · sugar · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	898	0.69	0.75	83	empty
2	223	0.54	0.77	36	XYP, AHR
3	234	0.54	0.77	38	XYP, AHR
4	84	0.47	0.82	16	empty
5	60	0.30	0.74	16	empty

Interfaces

1 interface between chains.

A–B · 1023 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

1QW8 · Crystal structure of a family 51 alpha-L-arabinofuranosidase in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Q9XBQ3 · AlphaFold monomer V2.0 prediction for intracellular exo… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9XBQ3
Elsewhere: RCSB PDB 1QW8 · PDBe 1QW8 · UniProt Q9XBQ3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.