MolNFT v1 · #1980 · protein
The E. COLI biotin holoenzyme SYNTHETASE(SLASH)BIO repressor crystal structure delineates the biotin and DNA- binding domains
1BIA · Bira bifunctional protein: “The E. COLI biotin holoenzyme SYNTHETASE(SLASH)BIO repressor crystal structure delineates the biotin and DNA…”. X-ray diffraction, 2 pockets (best druggability 0.57). MolNFT v1 #1980 on GenesisL1: 3D…
- PDB
- 1BIA
- Type
- protein
- Length
- 292 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bira bifunctional protein
- EC
- 6.3.4.15
- UniProt
- P06709
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bira bifunctional protein (EC 6.3.4.15) | protein | 292 | 33% helix, 29% strand | P06709 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 186 | 0.57 | 0.80 | 25 | empty |
| 2 | 68 | 0.29 | 0.74 | 20 | empty |
Compared structures
- 1BIA · The E. COLI biotin holoenzyme SYNTHETASE(SLASH)BIO repressor crystal structure delineates… · the same entry in another collection · chain A against A, TM-score 1.00
- P06709 · AlphaFold monomer V2.0 prediction for bifunctional LIGASE/REPRESSOR bira (P06709) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06709
- Elsewhere: RCSB PDB 1BIA · PDBe 1BIA · UniProt P06709
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