MolNFT v1 · #19795 · protein
Crystal structure of two central spectrin-like repeats from alpha- actinin
1QUU · Human skeletal muscle alpha-actinin 2: “Crystal structure of two central spectrin-like repeats from alpha- actinin”. X-ray diffraction, 1 pocket (best druggability 0.43). MolNFT v1 #19795 on GenesisL1: 3D structure, binding sites…
- PDB
- 1QUU
- Type
- protein
- Length
- 248 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Human skeletal muscle alpha-actinin 2
- UniProt
- P35609
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Human skeletal muscle alpha-actinin 2 | protein | 248 | 78% helix, 0% strand | P35609 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 84 | 0.43 | 0.79 | 20 | empty |
Compared structures
- 1QUU · Crystal structure of two central spectrin-like repeats from alpha-actinin · the same entry in another collection · chain A against A, TM-score 1.00
- P35609 · AlphaFold monomer V2.0 prediction for alpha-actinin-2 (P35609) · a predicted model of the same protein · chain A against A, TM-score 0.75
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35609
- Elsewhere: RCSB PDB 1QUU · PDBe 1QUU · UniProt P35609
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