MolNFT v1 · #19759 · protein

Crystal structure of the ap-2 clathrin adaptor alpha- appendage

1QTS · Ap-2 clathrin adaptor alpha subunit (alpha- adaptin C): “Crystal structure of the ap-2 clathrin adaptor alpha- appendage”. X-ray diffraction, 2 pockets (best druggability 0.38). MolNFT v1 #19759 on GenesisL1: 3D structure, binding…

PDB: 1QTS
Type: protein
Length: 247 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ap-2 clathrin adaptor alpha subunit (alpha- adaptin C)
UniProt: P17427
Pockets: 2 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ap-2 clathrin adaptor alpha subunit (alpha- adaptin C)	protein	247	19% helix, 43% strand	P17427

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	123	0.38	0.74	14	empty
2	62	0.35	0.77	16	empty

Compared structures

1QTS · Crystal structure of the ap-2 clathrin adaptor alpha-appendage · the same entry in another collection · chain A against A, TM-score 1.00
P17427 · AlphaFold monomer V2.0 prediction for ap-2 complex subunit alpha-2 (P17427) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P17427
Elsewhere: RCSB PDB 1QTS · PDBe 1QTS · UniProt P17427

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