MolNFT v1 · #19446 · protein
HRPABC14.4, essential subunit of human RNA polymerases I, II and III
1QKL · DNA-directed RNA polymerase II 14.4 kd polypeptide: “HRPABC14.4, essential subunit of human RNA polymerases I, II and III”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #19446 on GenesisL1: 3D structure, binding sites…
- PDB
- 1QKL
- Type
- protein
- Length
- 127 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA-directed RNA polymerase II 14.4 kd polypeptide
- EC
- 2.7.7.6
- UniProt
- P41584
- Pockets
- 1 · best druggability 0.32
Structure
solution nmr · 1 distinct chain · 20% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II 14.4 kd polypeptide (EC 2.7.7.6) | protein | 127 | 20% helix, 15% strand | P41584 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 75 | 0.32 | 0.74 | 12 | empty |
Compared structures
- 1QKL · hRPABC14.4, essential subunit of human RNA polymerases I, II and III · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41584
- Elsewhere: RCSB PDB 1QKL · PDBe 1QKL · UniProt P41584
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.