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HRPABC14.4, essential subunit of human RNA polymerases I, II and III

Analyse HRPABC14.4, essential subunit of human RNA polymerases I, II and III in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1QKL
Type: protein
Length: 127 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA-directed RNA polymerase II 14.4 kd polypeptide
EC: 2.7.7.6
UniProt: P41584
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 20% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase II 14.4 kd polypeptide (EC 2.7.7.6)	protein	127	20% helix, 15% strand	P41584

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	75	0.32	0.74	12	empty

Compared structures

1QKL · hRPABC14.4, essential subunit of human RNA polymerases I, II and III · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P41584
Elsewhere: RCSB PDB 1QKL · PDBe 1QKL · UniProt P41584

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