MolNFT v1 · #19434 · protein
The solution structure of the domain from MECP2 that binds to methylated DNA
1QK9 · Methyl-cpg-binding protein 2: “The solution structure of the domain from MECP2 that binds to methylated DNA”. Solution nmr, 1 pocket (best druggability 0.47). MolNFT v1 #19434 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1QK9
- Type
- protein
- Length
- 92 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methyl-cpg-binding protein 2
- UniProt
- P51608
- Pockets
- 1 · best druggability 0.47
Structure
solution nmr · 1 distinct chain · 15% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methyl-cpg-binding protein 2 | protein | 92 | 15% helix, 14% strand | P51608 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.47 | 0.84 | 18 | empty |
Compared structures
- 1QK9 · The solution structure of the domain from MeCP2 that binds to methylated DNA · the same entry in another collection · chain A against A, TM-score 1.00
- P51608 · AlphaFold monomer V2.0 prediction for methyl-cpg-binding protein 2 (P51608) · a predicted model of the same protein · chain A against A, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51608
- Elsewhere: RCSB PDB 1QK9 · PDBe 1QK9 · UniProt P51608
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