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The solution structure of the domain from MECP2 that binds to methylated DNA

Analyse The solution structure of the domain from MECP2 that binds to methylated DNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1QK9
Type: protein
Length: 92 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methyl-cpg-binding protein 2
UniProt: P51608
Pockets: 1 · best druggability 0.47

Structure

solution nmr · 1 distinct chain · 15% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methyl-cpg-binding protein 2	protein	92	15% helix, 14% strand	P51608

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	63	0.47	0.84	18	empty

Compared structures

1QK9 · The solution structure of the domain from MeCP2 that binds to methylated DNA · the same entry in another collection · chain A against A, TM-score 1.00
P51608 · AlphaFold monomer V2.0 prediction for methyl-cpg-binding protein 2 (P51608) · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51608
Elsewhere: RCSB PDB 1QK9 · PDBe 1QK9 · UniProt P51608

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