MolNFT v1 · #19287 · protein

Canine GDP-ran R76E mutant

1QG2 · Protein (ran): “Canine GDP-ran R76E mutant”. X-ray diffraction, 2 ligands (GDP, MG), 1 pocket (best druggability 0.39). MolNFT v1 #19287 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QG2
Type: protein
Length: 201 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (ran)
UniProt: P62825
Ligands: GDP, MG
Pockets: 1 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (ran)	protein	201	34% helix, 27% strand	P62825

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.39	0.76	17	empty

Compared structures

1QG2 · Canine GDP-ran R76E mutant · the same entry in another collection · chain A against A, TM-score 1.00
P62825 · AlphaFold monomer V2.0 prediction for GTP-binding nuclear protein ran (P62825) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P62825
Elsewhere: RCSB PDB 1QG2 · PDBe 1QG2 · UniProt P62825

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