MolNFT v1 · #19272 · protein

Glutaredoxin-1-ribonucleotide reductase B1 mixed disulfide bond

1QFN · Protein (glutaredoxin 1): “Glutaredoxin-1-ribonucleotide reductase B1 mixed disulfide bond”. Solution nmr. MolNFT v1 #19272 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QFN
Type: protein
Length: 110 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (glutaredoxin 1); Protein (ribonucleoside-diphosphate reductase 1)
EC: 1.17.4.1
UniProt: P68688, P00452

Structure

solution nmr · 2 distinct chains · 33% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (glutaredoxin 1)	protein	85	42% helix, 18% strand	P68688
B	Protein (ribonucleoside-diphosphate reductase 1) (EC 1.17.4.1)	protein	25	0% helix, 0% strand	P00452

Interfaces

1 interface between chains.

A–B · 781 Å² buried · 18 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1QFN · Glutaredoxin-1-ribonucleotide reductase B1 mixed disulfide bond · the same entry in another collection · chain A against A, TM-score 1.00
P68688 · AlphaFold monomer V2.0 prediction for glutaredoxin 1 (P68688) · a predicted model of the same protein · chain A against A, TM-score 0.82
P00452 · AlphaFold monomer V2.0 prediction for ribonucleoside-diphosphate reductase 1 subunit… · a predicted model of the same protein · chain B against A, TM-score 0.27

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P68688
Every structure of UniProt P00452
Elsewhere: RCSB PDB 1QFN · PDBe 1QFN · UniProt P68688 · UniProt P00452

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