MolNFT v1 · #19185 · protein
Crystal structures of adenine phosphoribosyltransferase from leishmania donovani
1QCC: “Crystal structures of adenine phosphoribosyltransferase from leishmania donovani”. X-ray diffraction, 2 pockets (best druggability 0.67). MolNFT v1 #19185 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1QCC
- Type
- protein
- Length
- 236 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adenine phosphoribosyltransferase
- UniProt
- Q27679
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Adenine phosphoribosyltransferase | protein | 236 | 36% helix, 23% strand | Q27679 |
Ligands and binding sites
- CIT · Citric acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 486 | 0.67 | 0.78 | 47 | CIT |
| 2 | 66 | 0.54 | 0.87 | 19 | empty |
Compared structures
- 1QCC · Crystal structures of adenine phosphoribosyltransferase from leishmania donovani · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q27679
- Elsewhere: RCSB PDB 1QCC · PDBe 1QCC · UniProt Q27679
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