MolNFT v1 · #191581 · protein

Monovalent cation binding in cubic insulin crystals

9INS · Insulin (chain a): “Monovalent cation binding in cubic insulin crystals”. X-ray diffraction. MolNFT v1 #191581 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 9INS
Type: protein
Length: 51 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Insulin (chain a); Insulin (chain B)
UniProt: P01315

Structure

x-ray diffraction · 2 distinct chains · 47% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Insulin (chain a)	protein	21	48% helix, 5% strand	P01315
B	Insulin (chain B)	protein	30	47% helix, 3% strand	P01315

Interfaces

1 interface between chains.

A–B · 803 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

9INS · Monovalent cation binding in cubic insulin crystals · the same entry in another collection · chain A against A, TM-score 1.00
P01315 · AlphaFold monomer V2.0 prediction for insulin (P01315) · a predicted model of the same protein · chain B against A, TM-score 0.38

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01315
Elsewhere: RCSB PDB 9INS · PDBe 9INS · UniProt P01315

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