MolNFT v1 · #191549 · protein

Precursor of the T152A mutant glycosylasparaginase from flavobacterium meningosepticum

9GAA · Protein (glycosylasparaginase): “Precursor of the T152A mutant glycosylasparaginase from flavobacterium meningosepticum”. X-ray diffraction, 6 pockets (best druggability 0.58). MolNFT v1 #191549 on GenesisL1: 3D structure, binding…

PDB: 9GAA
Type: protein
Length: 558 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (glycosylasparaginase)
EC: 3.5.1.26
UniProt: Q47898
Pockets: 6 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	Protein (glycosylasparaginase) (EC 3.5.1.26)	protein	279	34% helix, 26% strand	Q47898

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.58	0.86	19	empty
2	74	0.52	0.85	25	empty
3	189	0.47	0.75	39	empty
4	52	0.47	0.85	17	empty
5	95	0.39	0.77	19	empty

Interfaces

1 interface between chains.

A–C · 2011 Å² buried · 28 hydrogen bonds · protein-protein

Compared structures

9GAA · Precursor of the T152A mutant glycosylasparaginase from flavobacterium meningosepticum · the same entry in another collection · chain A against A, TM-score 1.00
Q47898 · AlphaFold monomer V2.0 prediction for N(4)-(beta-N- acetylglucosaminyl)-L-asparaginase… · a predicted model of the same protein · chain C against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q47898
Elsewhere: RCSB PDB 9GAA · PDBe 9GAA · UniProt Q47898

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