MolNFT v1 · #191207 · protein
Hydrophobic probe bound to streptavidin - 2
8AQJ: “Hydrophobic probe bound to streptavidin - 2”. X-ray diffraction, 1 ligand (N9O), 1 pocket (best druggability 0.46). MolNFT v1 #191207 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8AQJ
- Type
- protein
- Length
- 125 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Streptavidin
- UniProt
- P22629
- Ligands
- N9O
- Pockets
- 1 · best druggability 0.46
Structure
x-ray diffraction · 1 distinct chain · 8% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Streptavidin | protein | 125 | 8% helix, 54% strand | P22629 |
Ligands and binding sites
- N9O · 5-[(3~{A}~{S},4~{S},6~{A}~{R})-2-oxidanylidene-1,3, 3~{A},4,6,6~{A}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-[6-(dimethylamino)-1,3-bis(oxidanylidene) benzo[de]isoquinolin-2-yl]ethyl]pentanamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 109 | 0.46 | 0.79 | 22 | N9O |
Compared structures
- 8AQJ · Hydrophobic probe bound to Streptavidin - 2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22629
- Elsewhere: RCSB PDB 8AQJ · PDBe 8AQJ · UniProt P22629
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