MolNFT v1 · #191059 · protein

Crystal structure of human brachyury G177D variant in complex with molpolrt-039-246-810

7ZL2 · T-box transcription factor T: “Crystal structure of human brachyury G177D variant in complex with molpolrt-039-246-810”. X-ray diffraction, 1 ligand (UNL), 1 pocket (best druggability 0.42). MolNFT v1 #191059 on GenesisL1: 3D…

PDB: 7ZL2
Type: protein
Length: 171 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: T-box transcription factor T
UniProt: O15178
Ligands: UNL
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	T-box transcription factor T	protein	171	16% helix, 36% strand	O15178

Ligands and binding sites

UNL · Unknown ligand · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.42	0.83	23	empty

Compared structures

7ZL2 · Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O15178
Elsewhere: RCSB PDB 7ZL2 · PDBe 7ZL2 · UniProt O15178

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.