MolNFT v1 · #19078 · protein

NMR structure of human cofilin

1Q8X · Cofilin, non-muscle isoform: “NMR structure of human cofilin”. Solution nmr, 1 pocket (best druggability 0.38). MolNFT v1 #19078 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1Q8X
Type: protein
Length: 166 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cofilin, non-muscle isoform
UniProt: P23528
Pockets: 1 · best druggability 0.38

Structure

solution nmr · 1 distinct chain · 30% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cofilin, non-muscle isoform	protein	166	30% helix, 23% strand	P23528

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.38	0.75	27	empty

Compared structures

1Q8X · NMR structure of human cofilin · the same entry in another collection · chain A against A, TM-score 1.00
P23528 · AlphaFold monomer V2.0 prediction for cofilin-1 (P23528) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23528
Elsewhere: RCSB PDB 1Q8X · PDBe 1Q8X · UniProt P23528

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