MolNFT v1 · #19065 · protein
Solution structure of alpha subunit of human EIF2
1Q8K · Eukaryotic translation initiation factor 2 subunit 1: “Solution structure of alpha subunit of human EIF2”. Solution nmr, 2 pockets (best druggability 0.46). MolNFT v1 #19065 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1Q8K
- Type
- protein
- Length
- 300 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Eukaryotic translation initiation factor 2 subunit 1
- UniProt
- P05198
- Pockets
- 2 · best druggability 0.46
Structure
solution nmr · 1 distinct chain · 40% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Eukaryotic translation initiation factor 2 subunit 1 | protein | 300 | 40% helix, 20% strand | P05198 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 232 | 0.46 | 0.73 | 33 | empty |
| 2 | 126 | 0.43 | 0.77 | 24 | empty |
Compared structures
- 1Q8K · Solution structure of alpha subunit of human eIF2 · the same entry in another collection · chain A against A, TM-score 1.00
- P05198 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 2 subunit… · a predicted model of the same protein · chain A against A, TM-score 0.60
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05198
- Elsewhere: RCSB PDB 1Q8K · PDBe 1Q8K · UniProt P05198
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.