MolNFT v1 · #190550 · protein
Crystal structure of human mmp-2 catalytic domain in complex with inhibitor
7XGJ: “Crystal structure of human mmp-2 catalytic domain in complex with inhibitor”. X-ray diffraction, 4 ligands (GZS, H0F, CA). MolNFT v1 #190550 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7XGJ
- Type
- protein
- Length
- 511 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Ligands
- GZS, H0F, CA, ZN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 168 | — | — |
| B | — | protein | 165 | — | — |
| C | — | protein | 166 | — | — |
| D, E, F | — | protein | 4 | — | — |
Ligands and binding sites
- GZS · 4-[(4-phenoxyphenyl)sulfonylamino]butanoic acid · ligand · 3 copies · chains A, D, B, E, C, F
- H0F · 2-[(2~{S})-1-[(2~{S},3~{S})-3-methyl-2-(methylamino) pentanoyl]pyrrolidin-2-yl]ethanamide · ligand · 3 copies · chains A, D, B, C, E, F
- CA · Calcium ion · metal · 9 copies · chains A, B, C
- ZN · Zinc ion · metal · 6 copies · chains A, D, B, E, C, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7XGJ · Crystal structure of human MMP-2 catalytic domain in complex with inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7XGJ · PDBe 7XGJ
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