MolNFT v1 · #190474 · protein
Crystal structure of athppd-phenylpyruvate complex
7X8D · 4-hydroxyphenylpyruvate dioxygenase: “Crystal structure of athppd-phenylpyruvate complex”. X-ray diffraction, 2 ligands (PPY, CO), 2 pockets (best druggability 0.67). MolNFT v1 #190474 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7X8D
- Type
- protein
- Length
- 381 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 4-hydroxyphenylpyruvate dioxygenase
- EC
- 1.13.11.27
- UniProt
- P93836
- Ligands
- PPY, CO
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) | protein | 381 | 27% helix, 33% strand | P93836 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 433 | 0.67 | 0.79 | 38 | CO, PPY |
| 2 | 66 | 0.34 | 0.77 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7X8D · Crystal structure of AtHPPD-phenylpyruvate complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P93836
- Elsewhere: RCSB PDB 7X8D · PDBe 7X8D · UniProt P93836
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