UniProt P93836
4-hydroxyphenylpyruvate dioxygenase (P93836)
4-hydroxyphenylpyruvate dioxygenase (UniProt P93836), EC 1.13.11.27: 69 experimental structures on GenesisL1, 51 ligands bound, 79 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P93836
- Protein
- 4-hydroxyphenylpyruvate dioxygenase
- EC
- 1.13.11.27
- Experimental structures
- 69
- Predicted models
- 0
- Ligands
- 51
- Pockets
- 79 · 21 records with a druggable one
Structures
69 records of P93836 in the MolNFT archive: 69 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SP9 | 4-Hydroxyphenylpyruvate Dioxygenase | x-ray diffraction | A, B | — | — |
| 1SP9 | 4-hydroxyphenylpyruvate dioxygenase | x-ray diffraction | A, B | — | — |
| 1SQD | Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian… | x-ray diffraction | A | — | — |
| 1SQD | Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian… | x-ray diffraction | A | — | — |
| 1TFZ | Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures… | x-ray diffraction | A | — | — |
| 1TFZ | Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures… | x-ray diffraction | A | — | — |
| 1TG5 | Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with DAS645 | x-ray diffraction | A | — | — |
| 1TG5 | Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with DAS645 | x-ray diffraction | A | — | — |
| 5XGK | Crystal structure of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD) complexed… | x-ray diffraction | A, B, C, D | TYF, FE | 15 (best 0.77) |
| 5XGK | Crystal structure of arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (athppd) complexed… | x-ray diffraction | A, B, C, D | TYF, FE | — |
| 5YWG | Crystal structure of Arabidopsis thaliana HPPD complexed with Mesotrione | x-ray diffraction | A, B | CO, 92L | — |
| 5YWG | Crystal structure of arabidopsis thaliana hppd complexed with mesotrione | x-ray diffraction | A, B | CO, 92L | — |
| 5YWH | Crystal structure of Arabidopsis thaliana HPPD complexed with Y13508 | x-ray diffraction | A, B | FE, 92U | 4 (best 0.75) |
| 5YWH | Crystal structure of arabidopsis thaliana hppd complexed with Y13508 | x-ray diffraction | A, B | FE, 92U | — |
| 5YWI | Crystal structure of arabidopsis thaliana hppd truncated mutant complexed with ntbc | x-ray diffraction | A | CO, NTD | — |
| 5YWK | Crystal structure of arabidopsis thaliana hppd complexed with benquitrione-methyl | x-ray diffraction | A, B | CO, 92X | — |
| 5YY6 | Crystal structure of arabidopsis thaliana hppd truncated mutant complexed with benquitrione | x-ray diffraction | A | CO, 94L | — |
| 5YY7 | Crystal structure of arabidopsis thaliana hppd complexed with benquitrione | x-ray diffraction | A, B | CO, 94L | — |
| 6ISD | Crystal structure of arabidopsis thaliana hppd complexed with sulcotrione | x-ray diffraction | A, B | 5BQ, CO | — |
| 6J63 | Crystal structure of Arabidopsis thaliana HPPD complexed with NTBC | x-ray diffraction | A, B, C, D | FE, NTD | 15 (best 0.72) |
| 6J63 | Crystal structure of arabidopsis thaliana hppd complexed with ntbc | x-ray diffraction | A, B, C, D | FE, NTD | — |
| 6JX9 | Structure of Y17107 complexed hppd | x-ray diffraction | A | CQC, CO | — |
| 6LGT | Complex structure of hppd with an inhibitor Y16542 | x-ray diffraction | A | CO, ED3 | — |
| 6M6D | Structure of HPPD complexed with a synthesized inhibitor | x-ray diffraction | A | CO, NJX | — |
| 6M6D | Structure of hppd complexed with a synthesized inhibitor | x-ray diffraction | A | CO, NJX | — |
| 7CJK | Complex structure of athppd with inhibitor Y18093 | x-ray diffraction | A | G0X, CO | — |
| 7CQR | Complex structure of hppd with Y16550 | x-ray diffraction | A | CO, GEU | — |
| 7CQS | Complex structure of hppd with topramezone | x-ray diffraction | A | CO, GJL | — |
| 7E0X | Crystal structure of arabidopsis thaliana hppd complexed with 4- hydroxyphenylacetic acid | x-ray diffraction | A | CO, 4HP | — |
| 7EZQ | Complex structure of athppd with inhibitor Y15832 | x-ray diffraction | A | 0O0, CO | — |
| 7V6X | Crystal structure of HPPD complexed with Y18556 | x-ray diffraction | A | CO, 5RJ | — |
| 7V6X | Crystal structure of hppd complexed with Y18556 | x-ray diffraction | A | CO, 5RJ | — |
| 7VO8 | Structure of AtHPPD complexed with LSY-1 | x-ray diffraction | A | CO, 7RQ | 2 (best 0.69) |
| 7WJK | Complex structure of AtHPPD-ZWJ | x-ray diffraction | A | CO, 0I7 | 3 (best 0.68) |
| 7X5R | Crystal structure of AtHPPD-Lancotrione complex | x-ray diffraction | A | CO, 9P5, BCN | — |
| 7X5R | Crystal structure of athppd-lancotrione complex | x-ray diffraction | A | CO, 9P5, BCN | — |
| 7X5S | Crystal structure of athppd-Y14157 complex | x-ray diffraction | A | CO, 9QL | — |
| 7X5U | Crystal structure of athppd-diketonitrile complex | x-ray diffraction | A | CO, 9R6 | — |
| 7X5W | Crystal structure of athppd-Y18022 complex | x-ray diffraction | A | CO, 9US | — |
| 7X5X | Crystal structure of athppd-YH20533 complex | x-ray diffraction | A | CO, 9V4 | — |
| 7X5Y | Crystal structure of AtHPPD-Y14240 complex | x-ray diffraction | A | CO, HZS | 3 (best 0.70) |
| 7X5Y | Crystal structure of athppd-Y14240 complex | x-ray diffraction | A | CO, HZS | — |
| 7X5Z | Crystal structure of athppd-Y13162 complex | x-ray diffraction | A | CO, 9WC | — |
| 7X62 | Crystal structure of AtHPPD-Y191051 complex | x-ray diffraction | A | CO, 9XI | 2 (best 0.67) |
| 7X62 | Crystal structure of athppd-Y191051 complex | x-ray diffraction | A | CO, 9XI | — |
| 7X64 | Crystal structure of athppd-Y18027 complex | x-ray diffraction | A | CO, 9XU | — |
| 7X65 | Crystal structure of athppd-Y191052 complex | x-ray diffraction | A | CO, 9YI | — |
| 7X67 | Crystal structure of athppd-Y18406 complex | x-ray diffraction | A | CO, 9ZH | — |
| 7X69 | Crystal structure of athppd-Y191053 complex | x-ray diffraction | A | CO, 9ZO | — |
| 7X6M | Crystal structure of athppd-Y191058 complex | x-ray diffraction | A | CO, 9ZU | — |
| 7X6N | Crystal structure of athppd-Y191710 complex | x-ray diffraction | A | CO, A0M | — |
| 7X8D | Crystal structure of athppd-phenylpyruvate complex | x-ray diffraction | A | CO, PPY | — |
| 7X8H | Crystal structure of athppd-(+)-usnic acid complex | x-ray diffraction | A | CO, AIY | — |
| 7X8I | Crystal structure of athppd-shikonin complex | x-ray diffraction | A | CO, FNO | — |
| 7XVH | Crystal structure of AtHPPD-Y13287 complex | x-ray diffraction | A | CO, 92X | 2 (best 0.68) |
| 8HYS | Crystal structure of AtHPPD-Y19802 complex | x-ray diffraction | A | CO, O1O | 2 (best 0.68) |
| 8I2P | Crystal structure of AtHPPD-Y19060 complex | x-ray diffraction | A | CO, OAY | 2 (best 0.68) |
| 8I2S | Crystal structure of AtHPPD-Y18979 complex | x-ray diffraction | A | CO, T4I | 2 (best 0.70) |
| 8I2U | Crystal structure of AtHPPD-YH20282 complex | x-ray diffraction | A | CO, T5I | 2 (best 0.68) |
| 8J3C | Crystal structure of AtHPPD-Y19623 complex | x-ray diffraction | A | CO, SZO | 2 (best 0.67) |
9 records more on the page itself.
Ligands
- CO · Cobalt (II) ion · in 54 records
- FE · Fe (III) ion · in 6 records
- NTD · 2-{hydroxy[2-nitro-4-(trifluoromethyl) phenyl]methylene}cyclohexane-1,3-dione · in 3 records
- 5RJ · 5-methyl-3-[(2-methylphenyl)methyl]-6-[(1~{R},2~{S})-2-oxidanyl-6-oxidanylidene-cyclohexyl]carbonyl-1,2,3-benzotriazin-4-one · in 2 records
- 92L · 2-[(4-methylsulfonyl-2-nitro-phenyl)-oxidanyl-methylidene]cyclohexane-1,3-dione · in 2 records
- 92U · [1,3-diethyl-2,2-bis(oxidanylidene)-2$l^{6},1,3-benzothiadiazol-5-yl]-(1-methyl-5-oxidanyl-pyrazol-4-yl)methanone · in 2 records
- 92X · 1,5-dimethyl-3-(2-methylphenyl)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2, 4-dione · in 2 records
- 94L · 3-(2,6-dimethylphenyl)-1-methyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2, 4-dione · in 2 records
- 9P5 · (1R,3R)-2-[(S)-[2-chloranyl-3-[2-(1,3-dioxolan-2-yl) ethoxy]-4-methylsulfonyl-phenyl]-oxidanyl-methyl]cyclohexane-1,3-diol · in 2 records
- 9XI · 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-phenyl-quinazoline-2,4-dione · in 2 records
- BCN · Bicine · in 2 records
- HZS · (1R,3S)-5-methyl-2-[(1S)-2-naphthalen-1-yloxy-1-oxidanyl-ethyl]cyclohexane-1,3-diol · in 2 records
- NJX · 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(3-trimethylsilylprop-2-ynyl) quinazoline-2,4-dione · in 2 records
- TYF · (2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid · in 2 records
- 0I7 · 3-[2-[4-[[4-[2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-8-yl]phenoxy]methyl]-1,2,3-triazol-1-yl]ethyl]-1,5-dimethyl-6-[(1S)-2-oxidanyl-6-oxidanylidene-cyclohex-2-en-1-yl]carbonyl-quinazoline-2,4-dione · in 1 record
- 0O0 · 6-(1,3-dimethyl-5-oxidanyl-pyrazol-4-yl)carbonyl-1,5-dimethyl-3-(2-methylphenyl)quinazoline-2,4-dione · in 1 record
- 4HP · 4-hydroxyphenylacetate · in 1 record
- 5BQ · 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione · in 1 record
- 7RQ · N-[6-[[9-(dimethylamino)-12H-benzo[a]phenoxazin-5-yl]amino]hexyl]-4-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-[oxidanyl(oxidanylidene)-$l^4-azanyl]benzamide · in 1 record
- 9QL · 2-methyl-4-(2-nitro-4-piperidin-1-yl-phenyl)carbonyl-5-phenyl-1H-pyrazol-3-one · in 1 record
- 9R6 · (1R,2S,3R)-1-cyclopropyl-2-(iminomethyl)-3-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]propane-1,3-diol · in 1 record
- 9US · 1,5-dimethyl-3-naphthalen-1-yl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2, 4-dione · in 1 record
- 9V4 · 2-methylsulfonyl-N-(1-methyl-1,2,3,4-tetrazol-5-yl)-4-(trifluoromethyl)benzamide · in 1 record
- 9WC · 1-methyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-phenyl-quinazoline-2,4-dione · in 1 record
- 9XU · 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(phenylmethyl)quinazoline-2,4-dione · in 1 record
- 9YI · 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(2-phenylethyl)quinazoline-2,4-dione · in 1 record
- 9ZH · 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(3-phenylpropyl)quinazoline-2,4-dione · in 1 record
- 9ZO · 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(4-phenylbutyl)quinazoline-2,4-dione · in 1 record
- 9ZU · 5-methyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-phenyl-2-(trifluoromethyl)quinazolin-4-one · in 1 record
- A0M · Ethyl 5-methyl-4-oxidanylidene-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-phenyl-quinazoline-2-carboxylate · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.