MolNFT v1 · #189864 · protein
Glycosyltranferase UGT74AN2
7W0Z · Glycosyltransferase: “Glycosyltranferase UGT74AN2”. X-ray diffraction, 2 ligands (UDP, 6JI), 4 pockets (best druggability 0.77). MolNFT v1 #189864 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7W0Z
- Type
- protein
- Length
- 439 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycosyltransferase
- UniProt
- A0A385Z7H9
- Ligands
- UDP, 6JI
- Pockets
- 4 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycosyltransferase | protein | 439 | 46% helix, 17% strand | A0A385Z7H9 |
Ligands and binding sites
- UDP · Uridine-5'-diphosphate · ligand · chains A
- 6JI · 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011, 16]octadecan-6-yl]pyran-2-one · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 522 | 0.77 | 0.84 | 58 | UDP, 6JI |
| 2 | 112 | 0.43 | 0.77 | 16 | empty |
| 3 | 62 | 0.39 | 0.80 | 19 | empty |
| 4 | 68 | 0.38 | 0.79 | 17 | empty |
Compared structures
- 7W0Z · Glycosyltranferase UGT74AN2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A385Z7H9
- Elsewhere: RCSB PDB 7W0Z · PDBe 7W0Z · UniProt A0A385Z7H9
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