MolNFT v1 · #189835 · protein
Crystal structure of human TIGIT(23-129) in complex with the scfv fragment of anti-tigit antibody MG1131
7VYT: “Crystal structure of human TIGIT(23-129) in complex with the scfv fragment of anti-tigit antibody MG1131”. X-ray diffraction. MolNFT v1 #189835 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7VYT
- Type
- protein
- Length
- 674 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q495A1
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 105 | — | Q495A1 |
| B | — | protein | 120 | — | — |
| T | — | protein | 104 | — | Q495A1 |
| L | — | protein | 111 | — | — |
| H | — | protein | 121 | — | — |
| C | — | protein | 113 | — | — |
Ligands and binding sites
- FLC · Citrate anion · additive · 2 copies · chains T, H, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7VYT · Crystal structure of human TIGIT(23-129) in complex with the scFv fragment of anti-TIGIT… · the same entry in another collection · chain C against C, TM-score 1.00
- Q495A1 · AlphaFold monomer V2.0 prediction for T-cell immunoreceptor with ig and itim domains… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q495A1
- Elsewhere: RCSB PDB 7VYT · PDBe 7VYT · UniProt Q495A1
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