MolNFT v1 · #189550 · protein

Crystal structure of a bacterial SER/THR kinase

7VKC · HIPA_C domain-containing protein: “Crystal structure of a bacterial SER/THR kinase”. X-ray diffraction, 4 pockets (best druggability 0.67). MolNFT v1 #189550 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7VKC
Type: protein
Length: 316 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HIPA_C domain-containing protein
UniProt: Q5ZSZ6
Pockets: 4 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	HIPA_C domain-containing protein	protein	316	40% helix, 13% strand	Q5ZSZ6

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	178	0.67	0.87	30	empty
2	199	0.58	0.81	27	empty
3	53	0.52	0.88	18	empty
4	54	0.31	0.76	13	empty

Modifications

Observed in the structure: 7 modified (engineered, phosphorylation).

Compared structures

7VKC · Crystal structure of a bacterial Ser/Thr kinase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5ZSZ6
Elsewhere: RCSB PDB 7VKC · PDBe 7VKC · UniProt Q5ZSZ6

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