MolNFT v1 · #189492 · protein
Crystal structure of USP7-hubl domain
7VIJ · Ubiquitin carboxyl-terminal hydrolase 7: “Crystal structure of USP7-hubl domain”. X-ray diffraction, 4 pockets (best druggability 0.58). MolNFT v1 #189492 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7VIJ
- Type
- protein
- Length
- 529 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin carboxyl-terminal hydrolase 7
- EC
- 3.4.19.12
- UniProt
- Q93009
- Pockets
- 4 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 24% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) | protein | 529 | 24% helix, 32% strand | Q93009 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 224 | 0.58 | 0.80 | 30 | empty |
| 2 | 320 | 0.55 | 0.75 | 42 | empty |
| 3 | 80 | 0.39 | 0.78 | 16 | empty |
| 4 | 59 | 0.28 | 0.73 | 14 | empty |
Compared structures
- 7VIJ · Crystal structure of USP7-HUBL domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93009
- Elsewhere: RCSB PDB 7VIJ · PDBe 7VIJ · UniProt Q93009
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