MolNFT v1 · #189313 · protein

Crystal structure of the lanthipeptide zinc-metallopeptidase eryp from saccharopolyspora erythraea in closed state

7V9N · Alanine aminopeptidase: “Crystal structure of the lanthipeptide zinc-metallopeptidase eryp from saccharopolyspora erythraea in closed…”. X-ray diffraction, 2 ligands (ZN, CA), 8 pockets (best druggability 0.70). MolNFT v1 #189313 on…

PDB: 7V9N
Type: protein
Length: 859 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alanine aminopeptidase
EC: 3.4.11.2
UniProt: A4F9D7
Ligands: ZN, CA
Pockets: 8 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alanine aminopeptidase (EC 3.4.11.2)	protein	859	45% helix, 22% strand	A4F9D7

Ligands and binding sites

ZN · Zinc ion · metal · chains A
CA · Calcium ion · metal · chains A
GOL · Glycerol · additive · 3 copies · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	487	0.70	0.80	55	empty
2	484	0.70	0.80	49	CA
3	419	0.69	0.81	53	empty
4	141	0.43	0.75	28	GOL
5	58	0.37	0.79	20	empty

Compared structures

7V9N · Crystal structure of the lanthipeptide zinc-metallopeptidase EryP from saccharopolyspora… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4F9D7
Elsewhere: RCSB PDB 7V9N · PDBe 7V9N · UniProt A4F9D7

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