MolNFT v1 · #189160 · protein + RNA
Crystal structure of human ALKBH5 in complex with M6A-containing ssrna
7V4G: “Crystal structure of human ALKBH5 in complex with M6A-containing ssrna”. X-ray diffraction, 2 ligands (MN, SO4). MolNFT v1 #189160 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7V4G
- Type
- protein + RNA
- Length
- 652 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q6P6C2
- Ligands
- MN, SO4
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, E, F | — | rna | 4 | — | — |
| A | — | protein | 212 | — | Q6P6C2 |
| B, C | — | protein | 214 | — | Q6P6C2 |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 3 copies · chains A, B, C
- SO4 · Sulfate ion · ion · 3 copies · chains D, A, E, B, F, C
- GOL · Glycerol · additive · 4 copies · chains D, E, A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7V4G · Crystal structure of human ALKBH5 in complex with m6A-containing ssRNA · the same entry in another collection · chain C against C, TM-score 1.00
- Q6P6C2 · AlphaFold monomer V2.0 prediction for RNA demethylase ALKBH5 (Q6P6C2) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6P6C2
- Elsewhere: RCSB PDB 7V4G · PDBe 7V4G · UniProt Q6P6C2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.