MolNFT v1 · #189063 · protein

Crystal structure of omsk hemorrhagic fever virus NS5 mtase (in complex with sin)

7V1C · Core protein: “Crystal structure of omsk hemorrhagic fever virus NS5 mtase (in complex with sin)”. X-ray diffraction, 1 ligand (SFG), 2 pockets (best druggability 0.67). MolNFT v1 #189063 on GenesisL1: 3D structure, binding sites…

PDB: 7V1C
Type: protein
Length: 260 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Core protein
EC: 3.4.21.91, 3.6.1.15, 3.6.4.13
UniProt: C4TPE0
Ligands: SFG
Pockets: 2 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Core protein (EC 3.4.21.91, 3.6.1.15, 3.6.4.13)	protein	260	39% helix, 18% strand	C4TPE0

Ligands and binding sites

SFG · Sinefungin · ligand · chains A
PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	596	0.67	0.77	55	GOL, SFG
2	74	0.31	0.74	17	empty

Compared structures

7V1C · Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SIN) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C4TPE0
Elsewhere: RCSB PDB 7V1C · PDBe 7V1C · UniProt C4TPE0

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