MolNFT v1 · #189047 · protein
Local refinement of band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
7V0U · Band 3 anion transport protein: “Local refinement of band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex”. Electron microscopy, 4 pockets (best druggability 0.74). MolNFT v1 #189047 on GenesisL1: 3D structure…
- PDB
- 7V0U
- Type
- protein
- Length
- 558 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Band 3 anion transport protein
- UniProt
- P02730
- Pockets
- 4 · best druggability 0.74
Structure
electron microscopy · 2 distinct chains · 36% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| F | Band 3 anion transport protein | protein | 285 | 34% helix, 25% strand | P02730 |
| D | Band 3 anion transport protein | protein | 273 | 38% helix, 27% strand | P02730 |
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 493 | 0.74 | 0.82 | 52 | empty |
| 2 | 406 | 0.67 | 0.80 | 48 | empty |
| 3 | 76 | 0.60 | 0.89 | 21 | empty |
| 4 | 155 | 0.58 | 0.83 | 28 | empty |
Interfaces
1 interface between chains.
- F–D · 2648 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 7V0U · Local refinement of Band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1… · the same entry in another collection · chain F against F, TM-score 1.00
- P02730 · AlphaFold monomer V2.0 prediction for band 3 anion transport protein (P02730) · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02730
- Elsewhere: RCSB PDB 7V0U · PDBe 7V0U · UniProt P02730
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.