MolNFT v1 · #188936 · protein
Crystal structure of C-terminal domain of MSK1 in complex with in covalently bound literature RSK2 inhibitor pyrrolopyrimidine cyanoacrylamide compound 25 (co-crystal)
7UP6: “Crystal structure of C-terminal domain of MSK1 in complex with in covalently bound literature RSK2 inhibitor…”. X-ray diffraction, 2 ligands (OXM, SUU). MolNFT v1 #188936 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7UP6
- Type
- protein
- Length
- 257 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O75582
- Ligands
- OXM, SUU
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 257 | — | O75582 |
Ligands and binding sites
- OXM · Oxamic acid · ligand · 2 copies · chains A
- SUU · (E)-3-(3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)-2-cyanoacrylamide bound form · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7UP6 · Crystal structure of C-terminal domain of MSK1 in complex with in covalently bound… · the same entry in another collection · chain A against A, TM-score 1.00
- O75582 · AlphaFold monomer V2.0 prediction for ribosomal protein S6 kinase alpha-5 (O75582) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75582
- Elsewhere: RCSB PDB 7UP6 · PDBe 7UP6 · UniProt O75582
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