MolNFT v1 · #188874 · protein

Estrogen receptor alpha ligand binding domain in complex with RU39411

7UJO: “Estrogen receptor alpha ligand binding domain in complex with RU39411”. X-ray diffraction, 2 ligands (QYM, MG). MolNFT v1 #188874 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7UJO
Type: protein
Length: 938 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P03372
Ligands: QYM, MG

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	—	protein	234	—	P03372
D	—	protein	240	—	P03372
C	—	protein	233	—	P03372
A	—	protein	231	—	P03372

Ligands and binding sites

QYM · (9beta,11beta,17beta)-11-{4-[2-(dimethylamino) ethoxy]phenyl}estra-1,3,5(10)-triene-3,17-diol · ligand · 4 copies · chains B, D, C, A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7UJO · Estrogen Receptor Alpha Ligand Binding Domain in Complex with RU39411 · the same entry in another collection · chain A against A, TM-score 1.00
P03372 · AlphaFold monomer V2.0 prediction for estrogen receptor (P03372) · a predicted model of the same protein · chain B against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03372
Elsewhere: RCSB PDB 7UJO · PDBe 7UJO · UniProt P03372

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