MolNFT v1 · #188656 · protein

Crystal structure of human GSK3B in complex with G12

7U2Z: “Crystal structure of human GSK3B in complex with G12”. X-ray diffraction, 2 ligands (L7C, CL). MolNFT v1 #188656 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7U2Z
Type: protein
Length: 693 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P49841
Ligands: L7C, CL

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	345	—	P49841
B	—	protein	348	—	P49841

Ligands and binding sites

L7C · (3R)-1-[3-(2-fluorophenyl)propanoyl]-N-(pyridin-2-yl) pyrrolidine-3-carboxamide · ligand · 2 copies · chains A, B
CL · Chloride ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7U2Z · Crystal structure of human GSK3B in complex with G12 · the same entry in another collection · chain A against A, TM-score 1.00
P49841 · AlphaFold monomer V2.0 prediction for glycogen synthase kinase-3 beta (P49841) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49841
Elsewhere: RCSB PDB 7U2Z · PDBe 7U2Z · UniProt P49841

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