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Ligand · L7C

L7C · (3R)-1-[3-(2-fluorophenyl)propanoyl]-N-(pyridin-2-yl) pyrrolidine-3-carboxamide

L7C, (3R)-1-[3-(2-fluorophenyl)propanoyl]-N-(pyridin-2-yl) pyrrolidine-3-carboxamide (C19 H20 F N3 O2, 341.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
L7C
Formula
C19 H20 F N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

L7C in 2 structures; the first of them:

  • 7U2Z · Crystal structure of human GSK3B in complex with G12 · L7C A401 · binds ILE62, GLY63, ALA83, VAL110, LEU132, ASP133, TYR134, VAL135 and 4 more
  • 7U2Z · Crystal structure of human GSK3B in complex with G12 · L7C A401 · binds ILE62, ALA83, LEU132, ASP133, TYR134, VAL135, PRO136, THR138 and 2 more

Residues it binds most

LEU 4, VAL 4, ALA 4, ARG 4, ASP 4, GLY 3, ILE 4, PRO 4, THR 4, TYR 4 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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