MolNFT v1 · #188431 · protein

Crystal structure of the C-terminal ligand-binding domain of the lysr family transcriptional regulator yfba from yersinia pestis

7TRW · Lysr-family transcriptional regulatory protein: “Crystal structure of the C-terminal ligand-binding domain of the lysr family transcriptional regulator yfba…”. X-ray diffraction, 2 ligands (3HB, PO4), 1 pocket (best druggability…

PDB: 7TRW
Type: protein
Length: 213 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysr-family transcriptional regulatory protein
UniProt: Q8D0G2
Ligands: 3HB, PO4
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lysr-family transcriptional regulatory protein	protein	213	32% helix, 32% strand	Q8D0G2

Ligands and binding sites

3HB · 3-hydroxybenzoic acid · ligand · chains A
PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	464	0.71	0.81	49	3HB, PO4

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

7TRW · Crystal Structure of the C-terminal Ligand-Binding Domain of the LysR family… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8D0G2
Elsewhere: RCSB PDB 7TRW · PDBe 7TRW · UniProt Q8D0G2

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