MolNFT v1 · #188414 · protein
Crystal structure of histidine ammonia lyase from thermoplasma acidophilum
7TQR · Probable histidine ammonia-lyase: “Crystal structure of histidine ammonia lyase from thermoplasma acidophilum”. X-ray diffraction, 2 pockets (best druggability 0.37). MolNFT v1 #188414 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7TQR
- Type
- protein
- Length
- 484 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable histidine ammonia-lyase
- EC
- 4.3.1.3
- UniProt
- Q9HLI6
- Pockets
- 2 · best druggability 0.37
Structure
x-ray diffraction · 1 distinct chain · 63% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable histidine ammonia-lyase (EC 4.3.1.3) | protein | 484 | 63% helix, 6% strand | Q9HLI6 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.37 | 0.75 | 21 | empty |
| 2 | 83 | 0.35 | 0.75 | 19 | empty |
Modifications
Observed in the structure: 1 modified (nonstandard).
Compared structures
- 7TQR · Crystal Structure of histidine ammonia lyase from Thermoplasma acidophilum · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HLI6 · AlphaFold monomer V2.0 prediction for probable histidine ammonia- lyase (Q9HLI6) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HLI6
- Elsewhere: RCSB PDB 7TQR · PDBe 7TQR · UniProt Q9HLI6
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