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Crystal structure of histidine ammonia lyase from thermoplasma acidophilum

Analyse Crystal structure of histidine ammonia lyase from thermoplasma acidophilum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7TQR
Type: protein
Length: 484 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable histidine ammonia-lyase
EC: 4.3.1.3
UniProt: Q9HLI6
Pockets: 2 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 63% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable histidine ammonia-lyase (EC 4.3.1.3)	protein	484	63% helix, 6% strand	Q9HLI6

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.37	0.75	21	empty
2	83	0.35	0.75	19	empty

Modifications

Observed in the structure: 1 modified (nonstandard).

Compared structures

7TQR · Crystal Structure of histidine ammonia lyase from Thermoplasma acidophilum · the same entry in another collection · chain A against A, TM-score 1.00
Q9HLI6 · AlphaFold monomer V2.0 prediction for probable histidine ammonia- lyase (Q9HLI6) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HLI6
Elsewhere: RCSB PDB 7TQR · PDBe 7TQR · UniProt Q9HLI6

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