MolNFT v1 · #187987 · protein
Structure of active janus kinase (JAK) dimer complexed with cytokine receptor intracellular domain
7T6F: “Structure of active janus kinase (JAK) dimer complexed with cytokine receptor intracellular domain”. Electron microscopy, 2 ligands (ADN, ADP). MolNFT v1 #187987 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7T6F
- Type
- protein
- Length
- 2,164 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- B1ASP2, Q8CGK5
- Ligands
- ADN, ADP
Structure
electron microscopy · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 1045 | — | B1ASP2 |
| C, D | — | protein | 37 | — | Q8CGK5 |
Ligands and binding sites
- ADN · Adenosine · ligand · 2 copies · chains A, B
- ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7T6F · Structure of active Janus Kinase (JAK) dimer complexed with cytokine receptor… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8CGK5 · AlphaFold monomer V2.0 prediction for interferon lambda receptor 1 (Q8CGK5) · a predicted model of the same protein · chain C against A, TM-score 0.40
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B1ASP2
- Every structure of UniProt Q8CGK5
- Elsewhere: RCSB PDB 7T6F · PDBe 7T6F · UniProt B1ASP2 · UniProt Q8CGK5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.