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MolNFT v1 · #187706 · protein

Metal dependent activation of plasmodium falciparum M17 aminopeptidase (inactive form), spacegroup P22121

7SRV: “Metal dependent activation of plasmodium falciparum M17 aminopeptidase (inactive form), spacegroup P22121”. X-ray diffraction, 4 ligands (ZN, CA, CO3). MolNFT v1 #187706 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7SRV
Type
protein
Length
3,082 residues
Chains
6
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q8IL11
Ligands
ZN, CA, CO3, PO4

Structure

x-ray diffraction · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein519—Q8IL11
B—protein518—Q8IL11
C—protein524—Q8IL11
D—protein506—Q8IL11
E—protein513—Q8IL11
F—protein502—Q8IL11

Ligands and binding sites

  • ZN · Zinc ion · metal · 12 copies · chains A, C, B, D, F, E
  • CA · Calcium ion · metal · 12 copies · chains A, B, C, D, E, F
  • CO3 · Carbonate ion · ion · 6 copies · chains A, B, C, D, E, F
  • PO4 · Phosphate ion · ion · 2 copies · chains A, B, C, D, E, F
  • ACT · Acetate ion · additive · 8 copies · chains A, B, C, D, E, F
  • EDO · 1,2-ethanediol · additive · 6 copies · chains A, C, D, F
  • GOL · Glycerol · additive · chains D, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7SRV · Metal dependent activation of Plasmodium falciparum M17 aminopeptidase (inactive form)… · the same entry in another collection · chain A against A, TM-score 1.00

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