MolNFT v1 · #187635 · protein
Crystal structure of HIV-1 K103N, Y181C mutant reverse transcriptase in complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl) ETHOXY)PHENOXY)-7-fluoro-2-naphthonitrile (JLJ635), a non-nucleoside inhibitor
7SO6: “Crystal structure of HIV-1 K103N, Y181C mutant reverse transcriptase in complex with…”. X-ray diffraction, 2 ligands (M9A, MG). MolNFT v1 #187635 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SO6
- Type
- protein
- Length
- 922 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- M9A, MG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 527 | — | P03366 |
| B | — | protein | 395 | — | P03366 |
Ligands and binding sites
- M9A · 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl) ethoxy]phenoxy}-7-fluoronaphthalene-2-carbonitrile · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7SO6 · Crystal Structure of HIV-1 K103N, Y181C mutant Reverse Transcriptase in Complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 7SO6 · PDBe 7SO6 · UniProt P03366
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