MolNFT v1 · #187374 · protein
Crystal structure of T. brucei hypoxanthine guanine phosphoribosyltransferase in complex with (4S,7S)-7-hydroxy-4- ((guanin-9-YL)METHYL)-2,5-dioxaheptan-1,7-diphosphonate
7SB7: “Crystal structure of T. brucei hypoxanthine guanine phosphoribosyltransferase in complex with…”. X-ray diffraction, 1 ligand (8QI). MolNFT v1 #187374 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SB7
- Type
- protein
- Length
- 355 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q07010
- Ligands
- 8QI
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 177 | — | Q07010 |
| B | — | protein | 178 | — | Q07010 |
Ligands and binding sites
- 8QI · ({(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2S)-2-hydroxy-2-phosphonoethoxy]propoxy}methyl) phosphonic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7SB7 · Crystal structure of T. brucei hypoxanthine guanine phosphoribosyltransferase in complex… · the same entry in another collection · chain A against A, TM-score 1.00
- Q07010 · AlphaFold monomer V2.0 prediction for hypoxanthine-guanine phosphoribosyltransferase… · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07010
- Elsewhere: RCSB PDB 7SB7 · PDBe 7SB7 · UniProt Q07010
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