MolNFT v1 · #187345 · protein
Two-state solution NMR structure of apo PIN1
7SA5 · Peptidyl-prolyl cis-trans isomerase nima-interacting 1: “Two-state solution NMR structure of apo PIN1”. Solution nmr, 3 pockets (best druggability 0.61). MolNFT v1 #187345 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7SA5
- Type
- protein
- Length
- 163 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptidyl-prolyl cis-trans isomerase nima-interacting 1
- EC
- 5.2.1.8
- UniProt
- Q13526
- Pockets
- 3 · best druggability 0.61
Structure
solution nmr · 1 distinct chain · 12% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peptidyl-prolyl cis-trans isomerase nima-interacting 1 (EC 5.2.1.8) | protein | 163 | 12% helix, 17% strand | Q13526 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 133 | 0.61 | 0.85 | 21 | empty |
| 2 | 174 | 0.43 | 0.73 | 28 | empty |
| 3 | 100 | 0.41 | 0.76 | 19 | empty |
Compared structures
- 7SA5 · Two-state solution NMR structure of Apo Pin1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13526
- Elsewhere: RCSB PDB 7SA5 · PDBe 7SA5 · UniProt Q13526
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